Value of 21-gene Assay in Treatment Decisions for Hormone Receptor-positive Nodepositive Nodepositive
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Graphical Abstract
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Abstract
With the recently increasing number of the women newly diagnosed with early breast cancer(EBC),the 21-gene recurrence score assay has been clinically validated and recommended for the treatment decision making in patients with ER(+), node-negative(N0) EBC. A growing body of evidence from several large phase Ⅲ clinical trials reports similar findings in patients with ER(+), N(+) EBC. This assay could help guide treatment decisions for the patients who are most likely to receive benefit from chemotherapy.
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