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YAN Xiaolu, GAO Zhe, LI Qingxia. Clinical Significance of Serum Levels of IGF-1 and CA153 in Patients with Recurrence of Breast Cancer[J]. Cancer Research on Prevention and Treatment, 2015, 42(05): 481-482. DOI: 10.3971/j.issn.1000-8578.2015.05.013
Citation: YAN Xiaolu, GAO Zhe, LI Qingxia. Clinical Significance of Serum Levels of IGF-1 and CA153 in Patients with Recurrence of Breast Cancer[J]. Cancer Research on Prevention and Treatment, 2015, 42(05): 481-482. DOI: 10.3971/j.issn.1000-8578.2015.05.013
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Clinical Significance of Serum Levels of IGF-1 and CA153 in Patients with Recurrence of Breast Cancer

  • 1.Department of Oncology, The General Hospital of Hebei Province, Shijiazhuang 050051, China; 2. Department of Endocrinology, The General Hospital of Hebei Province,Shijiazhuang 050051, China

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  • Received Date: December 10, 2014
  • Revised Date: February 11, 2015
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    • Abstract
  • Objective To explore the clinical significance of serum IGF-1 and CA153 levels in patients with recurrence of breast cancer. Methods The serum levels of IGF-1 and CA153 in 169 patients with recurrence of breast cancer, 186 patients without recurrence of breast cancer were determined by ELISA and RIA respectively. Results The serum levels of IGF-1 and CA153 in patients with recurrence of breast cancer [(183.3±33.6), (75.8±6.7)] were significantly higher than those without recurrence of breast cancer [(89.7±21.5), (16.9±4.3) (P<0.05). And the serum levels of IGF-1 were positively correlated with the levels of CA153 (r=0.67, P<0.05). Conclusion The postoperative change of serum levels of IGF-1 and CA153 in patients with breast cancer might be helpful to predict the recurrence of breast cancer.
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    • References (8)
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