Human Hepatoma Membrane—associated Antigen Hab18g Is Identified As a CD147 Molecule
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Graphical Abstract
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Abstract
Objective To identify the Human hepatoma membrane-associated antigen Hab18g is a CD147 molecule from protein level,and the Hab18 and CD147mAb were used to investigate the epitope of antigen. Methods Indirect immunofluoscent;immunohistochemistry ABC method;dot blot and FCM additive test.Reaults Both CD147mAb and Hab18 recognize the same antigen,the mean intensity fluoresence of two kinds of antibodies used is higher than that of one antibody. Conclusion Human hepatoma membrane-associated antigen Hab18g may name as CD147 molecule,and two kinds of antibodies(Hab18 and CD147mAb)recognize the different epitope of the same antigen.
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