Multivariate Analysis of Clinicopathological Factors on Ureter Transitional Cell Carcinoma

Objective Our purpose was to evaluate the influence of various clinicopathologic factors on the survival of patients with ureter transitional cell carcinoma(TCC). Methods A computer analysis was performed on 51 patients underwent TCC resection . Results Univariate analysis identifi ed 7 factors that were associated with a significant outcome: Age（P=0.000）,clinical stage（P=0.004）,histologic type of lesion（P=0.000） and the way of surgical operation（P=0.048). The gender（P=0.655）, location of primary lesion（P=0.245） and pathology type of lesion（P=0.092） were not significantly associated with prognosis. However, when the interactive effects of these factors were taken into account,the clinical stage（P=0.021）,histologic type of lesion（P=0.001）,pathology type of lesion（P=0.048）and way of surgical operation（P=0.039）were selected as the most signifi cant prognostic factors in a multivariate analysis by using the Cox proportional hazard regression model. Conclusion In ureteral cancer surgery procedures design and choice, more importance should be attached to radical operation. On the prognosis improvement of patients with ureteral carcinoma, postoperative evaluation and treatment should refer to clinical stage, histologic type of lesion and pathology type of lesion.