A Randomized,Double-blinded,Drug-controlled and Multicentre Clinical Trial of Chemotherapy Assisted with Jinlong Capsule on Gastric Cancer

Objective To observe the therapeutic effect and security of chemotherapy assisted with Jinlong Capsule on patients with gastric cancer. Methods As a randomized,double-blinded,drug-controlled and multicentre study,141 gastric cancer patients diagnosed definitely by histopathology were randomly divided into experiment group (n=70) and control group (n=71).The chemotherapy (FOXFOL4 project or PF project for 2 circles) was used to all of the patients,and patients in experiment group or control group took Jinlong Capsule (4 pills once and 3 times per day) or Zhenqifuzheng Capsule (4 pills once and 3 times per day) orally,espectively.The course of treatment lasted 42 days. Results For the experiment group,the total therapeutic effective rate of the traditional Chinese medicine syndrome was 88.34%,the survival quality and body weight were improved respectively with 46.67% and 48.33%,while 59.68%,19.35% and 19.35% in control group,respectively(P<0.05).For some single symptoms of gastric cancer,the patients in experiment group also ameliorated better than that in control group.The objective therapeutic evaluation of tumor was 16.67% in experiment,while 8.33% in control group (P=0.0676).Furthermore,no serious adverse reaction was found in both two groups. Conclusion It is proved that the chemotherapy assisted with Jinlong Capsule has better therapeutic effect on patients with gastric cancer.