Observation of Short-term Efficacy of Intensity-modulated Radiotherapy for Middle Thoracic Esophageal Carcinoma

Objective To evaluate the short-term effect and adverse reactions of IMRT for middle thoracic esophageal carcinoma. Methods Fouty-one patients with middle thoracic esophageal carcinoma received IMRT with total prescription dose of 50~68 Gy and with 25~34 fractions.2.0 Gy/fraction，5 fractions/week. Results The overall response rate was 95.1% after radiotherapy and 92.7% 3 month respectively.The toxicities were acceptable except four patient with grade Ⅲ esophagitis and two patient with grade Ⅲ leukocytopenia. Conclusion The local control rate of middle thoracic esophageal carcinoma treated with IMRT was encouraging and this treatment was safe and reliable which might guarantee the completion of IMRT.