Clinical Characteristics and Survival Analysis of Basal-like Breast Cancer Patients
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Graphical Abstract
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Abstract
Objective To analyses the prevalence the clinical characteristics and survival time of Hui and Han patients with basal-like breast cancer in our hospital. Methods One hundred seventy one female breast cancer patients,were collected into this retrospective study.Basal-like breast cancer was defined by Nieslsen's method.Clinical characteristics,recurrence and metastatic time,and overall survival time were compared between basal-like and non- basal-like groups. Results basal-like breast cancer patients accounted for 15.3%(26/171).Compared with non- basal-like group,basal-like breast cancer had higher histologic tumor grade(69.23% vs.30.34%,P<0.001),less metastatic lymph nodes(34.62% vs. 58.62%,P=0.023),lower lymph nodes metastatic ratio(41.38% vs.65.38%,P=0.038).Basal-like breast cancer had a propensity for lung metastases.The five-year overall survival(OS) rates of basal-like and non- basal-like group were 70.3% and 87.9%,respectively.The five-year disease free survival(DFS) rates of two groups were 59.5% and 80.3%,respectively. Conclusion The prevalence of basal-like breast cancer was not markdedly different between Hui and Hanrace.Basal-like breast cancer had special clinical characteristics and poor survival.
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