Effect of Neo-adjuvant Chemotherapy with Surgery on Survival Ratio for Locally Advanced Non-small Cell Lung Cancer

ObjectiveTo investigate the effect of Neo-adjuvant chemotherapy for locally advanced non -small cell lung cancer survival ratio. Methods 119 patients with locally advanced non-small cell lung cancer were divided into two groups:group A (59 cases,preoperative neoadjuvant chemotherapy group) and group B(control group 60 cases without neoadjuvant chemotherapy).Compared with the difference of survival rate，effective ratio and post-operation complication of the patients. Results The total effective rate of preoperative neoadjuvant chemotherapy group was 54.23%（32/59），down regulation rate of stage was 20.33%（12/59）.Resective rate and radical rate of experimental group was 91.5％ and 81.4％,high than control group.The 1-，3-，5-year survival rates were 79.66%，50.88%，21.43% in group A,and 71.19%，35.09%，14.29% in group B,there was statistically significant between the two groups(P<0.05).The average survival time was 32.909 months in group A and 28.046 months in group B,there was statistically significant between the two groups(P<0.05). Conclusion Compared with the first-operation group，neoadjuvant chemotherapy followed up surgery have advantages for locally advanced non-small cell lung cancer patients,it didn't add surgical complication and it is still safe and feasible.