Clinical Observation of Iron Sucrose Combined with rHuEPO in Treatment of Cancer-related Anemia

ObjectiveTo investigate the curative effect, safety and impact of Iron Sucrose combined with rHuEPO on quality of life of cancer-related anemia. MethodsFifty-six cases of cancer-related anemia were randomly divided into two groups. The patients in EG were treated by Iron Sucrose, iv 100mg/d, 2d/w. The patients in CG were treated by Ferrous fumarate, p.o. 300mg tid. All patients were treated by rHuEPO ih 40 000 IU/w. The quality of life was measured by KPS. ResultsThe Hb, Hct, SF, TSAT（P<0.001）,the symptoms related to anemia and quality of life（P<0.05） of patients in EG were obviously improved, and had a lower IN of adverse effect（P<0.05）. ConclusionThe curative effect, safety and impact on quality of life of Iron Sucrose combined with rHuEPO on patients of cancer-related anemia were better than those of Ferrous fumarate combined with rHuEPO.