Expression significance of Src Family Throsine Kinase Fyn in Pulmonary Squamous Cell Carcinoma

Objective：To determine whether Fyn expression was altered in pulmonary squamous cell carcinoma (SCC) compared with pericancerous normal lung tissue (NORMAL). Methods ：We examined Fyn expression in pulmonary SCC and compared it to the normal lung tissue by immunohistochemical staining and immunoblotting. Results ：By immunohistochemical staining Fyn protein expression levels are increased in pulmonary SCC (12.54±2.45) compared to the NORMAL(4.34±1.27), P＜0.01.Meanwhile, we got the similar Results： by immunoblot analysis. Conclusion ：Fyn may act as an important molecule in the pulmonary SCC regulation.