Significance of Dendritic Cells Infiltration and HLA-DR Antigen Expressed in Gastric Cancer and Precancerous Lesions

Objective To study the clinical significance and effects of S-100 + DC infiltration and the expression of HLA-DR antigen in carcinogenesis and progression of gastric carcinoma. Methods S-100 + DC and HLA-DR antigen were detected in 43 specimens of gastric carcinoma,24 cases of precancerous lesions by immunohistochemical methods. Results The expression of S-100 + DC and HLA-DR in gastric carcinoma,precancerous lesions was markly higher than in normal gastric mucosa ( P < 0.05 ). The numbers of S-100...