Clinicopathologic Analysis of Patients with Breast Tumors in 6 207 Cases

Objective To try to find out the incidence,characteristics and regularity of breast tumors in past 27 years,This may offer valuable information for clinical and pathological doctors. Methods A statistic study was carried on 6 207 cases of breast tumors of the department of pathology in Tianjin Medical University General Hospital from January 1981 to December 2007.The statistic analysis was carried out by SAS 6.0 statistics software. Results The ratio of breast tumor to total tumor number and the ratio of the breast cancer to malignant tumors have been increasing(P=0.005,P=0.027) during past 27 years,The average age of breast benign and malignant tamors showed an increased trend.There was a little change in the histological types of the breast tumor among the three eras.The constituent ratios of the fibroadenoma and the intraductal papilloma increased in the breast benign tumor while the constituent ratios of the adenoma and the mesenchymoma decreased.Infiltrating duct carcinoma was still amajor type,but the constituent ratio of intraductal carcinoma increased, The constituent ratios of the adenocarcinoma and the medullary carcinoma decreased in the breast malignant tumor.The histological types of breast benign and malignant tumors both had significant difference（P<0.001）among the youngers, middle-aged and olders.In the breast benign tumor, the constituent ratio of fibroadenoma in the youngers was hiher than that in the middle-aged and olders.But the constituent ratios of the intraductal papilloma and the mesenchymoma were higher in the middle-aged and olders than in the youngers.In the breast malignant tumor, the constituent ratios of the phyllodes tumor and the infiltrating lobular carcinoma were higher in the youngers than in the olders. Conclusion The detection rate of breast tumors especially that of the breast malignant tumor increased, There was a little change in the histological types among the three eras.