Observation of Clinical Effect for Combination Therapy of Hyperthermia with GP on Advanced Breast Cancer

Objective To observe the clinical effect for combination therapy of hyperthermia with Gemcitabine plus Cisplatin on advanced breast cancer. Methods The results of 34 cases with advanced breast cancer underwent hyperthermia and GP combination therapy. The results were compared with those underwent GP chemotherapy alone. Results The hyperthermia and GP combination therapy group （58.8% and 76.5%）was superior to the GP group（41.1% and 35.3%）in effective rate and the life quality marks，which showed a significant difference（P<0.05）.The main toxicity was hemo-suppression and gastrointestinal toxicities. Conclusion Hyperthermia and GP combination therapy is efficient and safe for advanced breast cancer.