Study of the Expression of Human Chorionic Gonadotropin in Colorectal Diseases

Objective To study the expression and significance of HCG subunits in the colorectal diseases. Methods Streptavidin peroxidase immunohistochemical methods was used to detect the expression of HCG subunits. Results HCGα immunohistochemical positive cells only expressed in benign colorectal disease;The positive cells of HCGβ was rare in benign colorectal disease.Where as the expression rate of HCGβ was higher in colorectal carcinoma. Conclusion The distribution of the HCG subunits was different in the benign and malignant colorectal diseases.The expression of HCG β was associated with the differentiation and stage of the colorectal carcinoma,and its expression may be a reference to the malignance differentiation of the colorectal carcinoma.