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LIU Shan-lin, PENG Zhi-lan, LOU Jiang-yan, et al, . The Evaluation of Adenosine Triphosphate Bioluminescence Assay for Tumor in Vitro Chemosensitivity Test[J]. Cancer Research on Prevention and Treatment, 2000, 27(06): 429-432. DOI: 10.3971/j.issn.1000-8578.171
Citation: LIU Shan-lin, PENG Zhi-lan, LOU Jiang-yan, et al, . The Evaluation of Adenosine Triphosphate Bioluminescence Assay for Tumor in Vitro Chemosensitivity Test[J]. Cancer Research on Prevention and Treatment, 2000, 27(06): 429-432. DOI: 10.3971/j.issn.1000-8578.171
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The Evaluation of Adenosine Triphosphate Bioluminescence Assay for Tumor in Vitro Chemosensitivity Test

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  • Adanosine triphosphate(ATP) is the basic energy source for living cells.It rapidly disappears when cells die.So measuring the ATP levels may estimate the viability of cells exposed to drugs.Dose-response curve can be determined in mouse fibroma cell line:L929 treated with chemotherapeutic agents by the ATP-bioluminescence assay and The different in vitro response of 6 ovarian carcinoma (5 from fresh tumor tissues,1 from ascites)treated with etopside,cis-plating,5-fluorouracil and adriamycin can be investiga...
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