The Clinical Application of Penehyclidine Hydrochloride on the Neck and Maxillofacial Tumor before Operation

Objective 　To evaluate the effect of Penehyclidine hydrochloride on patients under going the tumor operation of neck and maxilla. Methods 　60 patient s with tumor of neck or maxilla were muscle injection 1mg of Penehyclidine hydrochloride 30 min before general anesthesia . To observing the amount of secretion of oral cavity and upper respiratory tract and sedation effect in the process inserting and pulling out t rachea or in the ICU. Results 　In the process of inserting t rachea through anesthesia, keeping anesthesia and consciousness, it had strong effect of secretion inhibition and central sedation. The secretion of oral and upper respiratory tract reduced obviously in ICU . 90 % of the patient s did not need to be given sedative. Conclusion 　Penehyclidine hydrochloride has st rong on secretion inhibition and cent ral sedation. Is is a better choice to be used in the tumor operation of neck and maxilla.