Combination of Urinary CYFRA21-1,Urinary Telomerase and VEGF to Detect Bladder Transitional Cell Carcinoma
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Graphical Abstract
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Abstract
Objective To explore the value of combined determination of urinary tumor markers for bladder transitional cell carcinoma(BTCC), which reflects the different stages of tumor genesis and progress. Methods Voided urine samples of 45 patients with BTCC were collected and divided into different aliquots for each tumor marker analysis. CYFRA21-1 and VEGF were measured by ELISA, telomerase was determined by TRAP. The sensitivity of combined determination was compared with that of individual tumor marker and u...
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