Clinicopathological Study on c-erbB-2,Metastasis-associated Protein 1 (MTA1) and E-cadherin Expression in Gastric Cardia Cancer

Objective To investigate the expression of c-erbB-2, MTA1 and E-cadherin and relationship between the expression of these proteins and the tumor biological behavior,as well as relationship between these proteins in gastric cardia cancer. Methods Immunohistochemical technique was used to detect the expression of c-erbB-2, MTA1 and E-cadherin among 60 gastric cardia cancer samples and 18 cases of adjacent mucosa tissue. Results c-erbB-2 over-expression was positively correlated with the depth of invasion, lymph...