Recent Thymic Output Function in Patients with Chronic Myelogenous Leukemia by Real Time PCR Analysis
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Graphical Abstract
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Abstract
Objective To quantitative analysis the T cell receptor excision DNA circles (TRECs) in CD3 +, CD4 + or CD8 + T cells, evaluating the thymic recent output function in patients with chronic myelogenous leukemia (CML). Methods Quantitative detection of T cell receptor excision DNA circles (TRECs) in DNA of peripheral blood mononuclear cells from 8 cases with CML, CD4 + or CD8 + cells from 3 cases with CML were preformed by real time PCR (TaqMan) analysis. And the TRECs number was related to the numbe...
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