Expression of iNOS and COX-2 in pancreatic adenocarcinoma and its clinical significance

Objective To investigate the expression of iNOS and COX-2 with clinicobiological behavior in human pancreatic adenocarcinoma and explore their correlation as well. Methods The expression of iNOS and COX-2 in 51 cases of human pancreatic ductal adenocarcinoma were detected with immunohistochemistry by Envision. Results Expression of iNOS and COX-2 in pancreatic ductal adenocarcinoma were 62.7%, 74.5%, respectively; no expressions of iNOS and COX-2 in adjacent normal tissue were detected. The iNOS ex...