Expression of uPA and VEGF: Association with Invasion and Metastasis in Nasopharyngeal Carcinoma
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Graphical Abstract
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Abstract
Objective To investigate the relationship between expression of uPA (urokinase type plasmiongen activator,uPA)and VEGF(Vascular endothelial growth factor,VEGF)and invasion and metastasis of nasopharyngeal carcinoma (NPC). Methods Expression of uPA and VEGF using immunohistochemical LASB stainning,Paraffin embedded specimens of 45 patients with NPC were detected.All ptients were folowed up 3 years. Results The positive rate of uPA and VEGF were significantly higher in cases with recurrence (R NPC) and in ca...
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