Association between Epste in-Barr Virus and no-Hodgkinp's Lymphomas
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Graphical Abstract
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Abstract
Objective To explore the relationship between NHL and EBV. Methods In 180 cases of NHL,the presence of EBV encoded small RNA(EBER1/2) was detected by ISH. Results (1)EBER1/2 positivity was found in 77 of 180(42.8%) NHLs, including 64.8% of TCLs,46.2% of NK/T cell lymphomas and 9.5% of BCLs.The positive rates of EBER1/2 in TCLs and NK/T cell lymphomas were significantly higher than that in BCLs ( P <0.005);(2) There was a significant difference in the positive rates of EBER1/2 in intra (22.2%) and extr...
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