Expression of pRb2/p130, cyclinD1 and MUC1 in Esophageal Squamous Cell Carcinoma
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Graphical Abstract
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Abstract
Objective To investigate the expressions and significance of pRb2/p130, cyclinD1 and MUC1 in esophageal squamous cell carcinoma. Methods Immunohistochemical method was used to detect the expressions of pRb2/p130, cyclinD1 and MUC1in 16 cases of normal mucosae epithelium of esophagus and 60 cases of squamous cell of esophageal carcinoma. Results Low pRb2/p130 expression in squamous cell of esophageal carcinoma was significantly associated with tumor differentiation, TNM stages, lymph-node metastasis and dept...
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