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HUANG Xuan, DIAO Lu-ming, DENG Hao, ZHOU Hong-yan, CHEN Ying, LIU Li-jiang. Using Tissue Microarray Technique Research the Expression Meaning of hMSH2 andp16INK4a in Gastric Cancer[J]. Cancer Research on Prevention and Treatment, 2005, 32(05): 273-273. DOI: 10.3971/j.issn.1000-8578.1271
Citation: HUANG Xuan, DIAO Lu-ming, DENG Hao, ZHOU Hong-yan, CHEN Ying, LIU Li-jiang. Using Tissue Microarray Technique Research the Expression Meaning of hMSH2 andp16INK4a in Gastric Cancer[J]. Cancer Research on Prevention and Treatment, 2005, 32(05): 273-273. DOI: 10.3971/j.issn.1000-8578.1271
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Using Tissue Microarray Technique Research the Expression Meaning of hMSH2 andp16INK4a in Gastric Cancer

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  • Objective 　This study was to investigate the expression meaning of hMSH2 and p16INK4a in gastric cancer. Methods 　Gastric cancer tissue microarray(TMA) was formed and tested expression of hMSH2 and 16INK4a by immunohistochemical methods. Results 　In gastric cancer, the overexpression rates of hMSH2 and 16INK4ashowed a positive correlation ( r = 0. 23507, P = 0. 0134), which were not related to lymph node metastasis, UICC N stage and prognosis. Conclusion 　the overexpression rates of hMSH2 and 16INK4a showed a positive correlation and both were not as molecule mark to predict lymph node metastasis, UICCN stage and prognosis.
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