Effects of fluorouracil or vincristine treatment combined with nordihydroguaiaretic acid on the human malignant glioma cell line

Objective To observe the effect of Fluorouracil or Vincristine treatment combined with Nor- dihydroguaiaretic acid on the human malignant glioma cell line. Methods The effect of drugs on the cells was measured by MTT, and the protein expression of cyclin Dl gene in the cells was measured by immuno- histochemistry. Results (1) The anti-tumor effects of drugs on the cells were dosedependent, and had a co- operative function between NDGA and 5-Fu or VCR. (2) There was not di...