Expression of c-erbB-2 and nm23 Protein in Breast Neoplasm and Their Clinical Significance

Objective To study the expression and clinical significance of c-erbB-2 and nm23 protein in breast neoplasm. Methods 131 cases of benign and malignant breast neoplasm were examined by immunohistochemical S-Pmethods.Among them,102 cases of breast carcinomas were examined for estrogen and progesterone receptor status. Results There was a high expression of c-erbB-2 in intraductal carcinoma,Pagets disease and infiltrating duct carcinoma. There was a high nm23 expression in infiltrating lobular carcinoma.There w...