The Inhibitory Effect of OK-432 and IL-2 on Lewis Lung Cancer Growth and c-fos Expression

ZHOU Jie; SHI Zao-xue; DONG Hong-ling; et al

doi:10.3971/j.issn.1000-8578.1206

ZHOU Jie, SHI Zao-xue, DONG Hong-ling, et al, . The Inhibitory Effect of OK-432 and IL-2 on Lewis Lung Cancer Growth and c-fos Expression[J]. Cancer Research on Prevention and Treatment, 2000, 27(06): 436-438. DOI: 10.3971/j.issn.1000-8578.1206

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The Inhibitory Effect of OK-432 and IL-2 on Lewis Lung Cancer Growth and c-fos Expression

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Objective To study the inhibitory effect of OK-432 and IL-2 on the growth of Lewis lung cancer (LLC) bearing C 57 BL/6 mice and c-fos protein expression. Methods As C 57 BL/6 mice bearing LLC model,we observed the effect of OK-432 in combination with IL-2 on the tumor occurrence,growth,metastasis,and the expression of c-fos by using the semiquantitative SABC immunohistochemical method. Results Combination group significantly enhanced inhibitory effect on tumor volume and weight versus control( P <...

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The Inhibitory Effect of OK-432 and IL-2 on Lewis Lung Cancer Growth and c-fos Expression

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