Recombinant tumor necrosis factor, interleukin-2, and interferon-γ effects on nasopharyngeal carcinoma cell in vitro and in vivo

JIAO Wei; DENG Zhuo-lin; LIU Shi-cai

doi:10.3971/j.issn.1000-8578.109

JIAO Wei, DENG Zhuo-lin, LIU Shi-cai. Recombinant tumor necrosis factor, interleukin-2, and interferon-γ effects on nasopharyngeal carcinoma cell in vitro and in vivo[J]. Cancer Research on Prevention and Treatment, 2002, 29(01): 15-17. DOI: 10.3971/j.issn.1000-8578.109

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Recombinant tumor necrosis factor, interleukin-2, and interferon-γ effects on nasopharyngeal carcinoma cell in vitro and in vivo

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Objective To experiment the anti-nasopharyngeal carcinoma activity of several cytokines of high anti-tumor effect. Methods Nasopharyngeal carcinoma cell line (CNE3) was established in our labora- tory . CNE3 in vitro and in nude mice bearing on subcutaneous were treated with the reagents of recombi- nant human tumor necrosis factor (rhTNFα), recombinant human interleukin-2 (rhIL-2) and interferon-γ (IFNY) singly or combinationally. Results CNE3 cells were very sensitive t...

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Recombinant tumor necrosis factor, interleukin-2, and interferon-γ effects on nasopharyngeal carcinoma cell in vitro and in vivo

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