Detecting Problematic Proliferative Lesions of Lymph Tissue by IgH and TCR Gene Rearrangement Technique

Objective To investigate the significance in diagnosis of problematic proliferative lesions of lymph tissue by IgH, TCR gene rearrangement technique. Methods Thirty-six cases of proliferative lesions of lymph tissue with diagnostic difficulty by routine HE and immunohistochemistry, were analyzed in detail by PCR-based IgH, TCR gene rearrangement technique to further determine the diagnosis. 20 cases of previously diagnosed lymphoma and 10 reactive lymphadenitis were used as a positive control and negative co...