Expression and Clinical Pathology of eIF4E and cyclin D1 in Gastric Carcinoma
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Graphical Abstract
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Abstract
Objective To study the expression of eukaryotic initiation factor 4E (eIF4E) and cyclin D1 in gastric carcinoma and its clinical significance, to evaluate the relationship between eIF4E and cyclin D1. Methods The expressions of eIF4E and cyclin D1 were detected in 91 cases of gastric carcinoma and 30 cases of normal gastric tissue by immunohistochemical method. Results The expression of eIF4E and cyclin D1 was negative in normal gastric tissue. The positive rate of eIF4E and cyclin D1 was 95.6% (87/91) and 8...
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