婚姻状态对肺癌患者生存预后的影响——基于SEER数据库的研究

Effect of Marital Status on Survival of Lung Cancer Patients Investigated Based on SEER Database

摘要:
目的研究婚姻状况是否是影响肺癌患者生存预后的独立因素。
方法采用Kaplan-Meier法对性别、年龄、种族、手术与否、肿瘤不同分化程度、TNM分期以及不同婚姻状态七个因素做单因素生存率分析；Cox多因素分析研究不同婚姻状态下肺癌患者的全因死亡率变化。
结果已婚患者的生存率（34.5%）在单因素分析下均优于单身组（28.9%）、丧偶组（28.3%）以及离异或分居组（32.6%），多因素分析亦如此。
结论婚姻状态是肺癌患者生存预后的影响因子之一。

Abstract:
Objective To assess the effect of marital status on the survival of patients with lung cancer.
Methods Kaplan-Meier test and Log rank test were used for the univariate analysis of gender, age, race, surgery or not, tumor grade, TNM degree and marital status. In multivariate analysis, Cox regression was used to analyze the all-cause mortality of patients with lung cancer under different marital status.
Results Married patients had higher survival rate(34.5%) than those who were never married(28.9%), widowed(28.3%) and divorced or separated(32.6%) in the univariate analysis. We could find the same results in the multivariate analysis.
Conclusion Marital status could affect the survival of lung cancer patients.