Abstract: Generally, in order to prevent rejection of grafts, immune inhibitors such as CsA are used to suppress lymphocytes function of recipients. But in this report we transplanted xenogeneic spleen cills or tumor cells with BCG on mice, by means of this to suppress tumor growth of recipient mice. The results showed that the survial time of the tumor bearing mice with ERI were significantly longer than of control group and suggest that the ERI might be used as a new metod of immunotherapy to treat and prevent cancer.