Abstract: From 1971-1987, 8 patients with primary carcinoma of the female urethra were treated in our Hospital. The ages ranged from 41-63, with an average of 53year. 7 cases were anterior urethra lesions, 1 case was posterior urethra lesions.Pathologic features showed 5 cases were adenocarcinoma. 2 cases squamous cellcarcinoma, 1 was transitional cell carcinoma. 3 cases were treated with irradiationalone, of these, 2 cases died of disease at 18, 11 months after treatment respectively, 1 case was lost of follow-up; partial urethrectomy plus radiation in one, whois still live and well about 15 months after treatment; 3 cases using bladderperformed total urethrectomy and reconstructed a new urethra in the origin positionflap, all have shown satisfactory results in short time;one case was untreated.The authors belive, operation is a chief therapeutic method for this diseasetotal urethrectomy and reconstructed of a new urethral is an ideal method at thepresent time.