Abstract: Resected specimens from 70 cases with primary gastric cancer. 79 cases with colorectum cancer, 3 cases with pancreas cancer and one cases with rectummelanoma were examined for the presence of estrogen and progesterone receptorER, PgR) with a fluorescent estradiol histochemical technique. In 70 primarygastric cancer, ER and PgR-positive incidence were 25.7%,31.4%respectively. Recep-tor positive incidence of cardia cancer was higher than other locations,and diffusetype was higher than other types. In 79 colorectum cancer, ER and PgR-positiveincidence were 31.7%, 34.2%respectively. ER and PgR-positive incidence of rectumcancer was higher than other locations.