Abstract: During the period of 1975-1985,170 patients with stomach cancer were treated by surgery plus chemotherapyor surgery alone randomly,After 5-year follow-up,the results are pre-sent as follows; 5-year survival rate for combinative therapeutic group was 40.2% (33/82), for contol group was 21,6% (19/88)，P<0.01,The median survival time for former group was 39 months，for latter was 18months only,The five year survival rate and the median survival time, or the patients who treated by radical operation and chemotherapy were 56,4% (31/55)and 45 months respectively,but for control group were 30,2% (19/63) and 23 mon-the (P<0.01)。The 5一year survival rate for patients with Stages II or III，the combinative therapeutic group was 60.5% (26/43)，the control group was 36,9%(17/46),These results suggested that radical operation combined with chemotherapy would be an effecitve method to enhance the survival time。