Abstract: The article dwells on the detection of urinary polyamines in combihation with the gastroscopic general screening to detect the levels of urinary polyamines of varied pol.ulation greups lliving in the high-incidence areas of esophageal cancer and gastric cancer. Findings confirmed that the levels of urinary polyatnines were closely correlated with the extent of canceration oI the histocytes of the esophagus and the stomach, Wren atypical proli-feration developed, an apparent increase in such polyamines (80.33- 115.15% having a positive rate of 100%) was detected.In cases of canceration, the elecation could be as high as 160.62-213.75%; positive rate: 100%. Such detection constitute a plain, possible, sensitive and reliable method that can easily be accepted by the patients with potential and symptomless esaphageal cancer and gastric cancer of the early stage and by precancerous patients (cases of atypical proliferation).