Abstract: From April 1984 to April 1990, 23 cases of esophageal cancer accompanied with the repeated cancer of the other organ's. 9 cases suffered from double primary malignant tumor simultaneously, 14 cases different time. The secondary cancer included 4 cases cardiac cancer, 6 cases gastric cancer, 2 cases colonic cancer, 6 cases lung cancer, 2 case skin cancer, 2 cases thyroid cancer, laryngeal cancer, nasopharynx cancer and cystic cancer 1 casese for respective. Esophageal cancer 17 cases by radiltherapy, 4 cases by surgery, 2 cases by chemotherapy, 2 cases by Chinese medicine. 1, 3 and 5 year survival rates were 34.8%, 8.7% and 6.3% respective1y. The prognosis related interval time of the Location of secondary, interval time of the secondary primary cancer and factor of esophageal cancer itself.