Abstract: From 1986 to 1991, the Chemotherapy Department of our hospital applied CE (A) F scheme to cure breast cancer in later period, breast cancer of relapse in part and transfered breast cancer. In this essay. 75 eases of the curative effect of the scheme are introduced. All the cases are women. The average age is 48. The curative effect evaluated according to WHO standard. The effective rate after the medicine is given is (CR+PR) 68% (51+75). The minority of the patients show bone marrow inhibition and side effect of gastrointestinal tract and etc. All this can be remission through general treatment. The advantage of the scheme is lower virulence, better effect, the time span of remission is long. The scheme can be usesd as routine treatment scheme. Based on the scheme, combined with thoracocentensis and pericardicentensia + injection in body cavity and radiotherapy to the nidus transfered to bone and brain, this scheme has the better curative effect. It is also effective to the psxieuts who have cuelomic fluid and have cancer transfered widely.