双途径介入治疗晚期肺癌

Two Route Interventional Chemotherapy in the Treatment of Later Lung Cancer

摘要: 我们自1990年至1993年, 对87例晚期肺癌患者采用支气管动脉及肺动脉双途径介入化疗, 收到满意疗效。术后平均生存18个月。与此同期单纯支气管动脉介入200例, 术后平均生存10.5个月, 经过双途径介入化疗大部分病人临床症状缓解, 提高了生活质量, 部分病人重新获得了手术机会, 生存期较单纯支气管动脉介入明显延长。表明肺动脉与支气管动脉同时介入, 较单纯支气管动脉介入化疗疗效好, 可以互相弥补其不足, 更广泛地杀死癌细胞。是一种有效的姑息治疗手段。

Abstract: cases of later lung cancer were treated by Two Route arterial Chemotherapy (TRAC) viabronchial artery and pulmonary artery. They were all stage Ⅲ-Ⅳ cases (TNM stages) in thisgroup. Selective bronchial arteriography showed the tumer's nourishing blood vessels. TRIC wasperformed injection the bronchial artery with CBP 300mg, ADM 30mg and VP-16 300mg; followed injection the pulmonary artery with VCR ling and MMC 4mg, 5-Fu 500mg etc for ten days. Goood results were achieved CR 90.87% of cases; PR 55.17%; MR 35.63%; NC 5.7%, PD 3.4%. TRAC was an effective palliative treatment way in later lung cancer.