Abstract: patients with lung cancer who recieved transthoracic needle biopsy is rported. There were 77 patients with peripheral lung cancer, 12 patients with central lung cancer and 3 patients with bilateral lung cancer. Maximum mass was 10.0×10.0cm, minimal mass was 1.5×1.0cm. Cancer cells were found in 84 patients, the positive rate was 91.3%. Majar complication was pneumothorax, rate of which was 9.8%. The experience which increased positive rate of biopsy was introduced.