Abstract: Abstract From October 1988 to October 1993, we performed pericardiocentesis and combined chemotherapy inside pericardium on the basis of MF scheme for 12 patients with lung cancer. We gained satisfactory effect. We prescribed medicine 1 to 3 times, the majority patient's dropsy were controled. 6 cases were CR, 4 cases were PR, 2 cases were NC. Thereforce we can lengthen the patient's survival time. We observed that the side effect of this scheme was light, systemic affect was minimum. It is not only coordinate stronger systemic chemotherapy, but also economical. It's trauma is minor and curative effect is reliable. It can be regarded as one of the good therapic method.