宫颈鳞状细胞癌雌、孕激素受体水平与预后的关系—附126例临床病理分析

Correlation between estrogen and progesterone receptor levels in the squamous cell carcinoma of the cervix and prognosis

摘要: 本文采用酶联亲和组化标记法测定了126例宫颈鳞状细胞癌雌激素受休(ER)，并对其中94例浏定了孕激素受休((PR ).结果表明:ER阳性率44.400(56/126), PR阳性率30. 8写(29/94), ER, PR皆阳性率24. 4 0o (23/94). ER,PR水平与病理组织学分级(P<0.01, P<0.05)及生存率(P<0. 05)均有明显的关来，这说明ER, PR水平越高，癌组织的分化程度越高，其生存期越长.因此，浏定宫颈癌ER, PR对判断预后及指导临床选择性内分泌治疗均有重大作用.

Abstract: The estrogen receptors (ER) in the 126 cases of squamous carcinoma of the cervix were deter-mined with enzyme-linking affinity immunohistochemistry method. The progesterone receptors(PR) were done in 94 of the 126 cases. The results showed that positive rates of ER and PR were44. 4% and 30. 8%.The positive rates of both ER and PR were 24. 4 % . ER and PR levels were sig-nificantly related to histological grades and surviving rates. it is indicated that the higher the ER andPR levels, the better the differetiated degree of cancer cells and the longer the survival.