Abstract: The influence of recurrent time, location, frequency as well as dose of re-irradiation to survival for 145 cases with recurrent nasopharyngeal cancer after first ridical irradiation was analyzed. All 10-year survival rate and 5-year survival rate after re-irradiation were 9.7% and 12.4% respectively. In the patientswith recurrence occured more than 3-year after first radical irradiation, 10-year survival rate was higher than that of other groups (P＜0.025 ). In the patients with recrrence occured only in the cervical lymph node, the 10-year survival rate was higherthan that with recurrence in nasopharyngeal (P＜0.05). There was an higher rate ofrepeated recurrence of the same place in this series. We believe that it is necessary toemphasize the importance of the first radical irradiation and that optional re-irradiation dose for the nasopharyngeal recurrence is 60-70Gy, and the one more than 70 Gyis liable to imerease the complication without improvement of the survival.