榄香烯乳合并化疗治疗原发性肺癌的临床观察

The Clinical Study On The Plan Of Elemene Emulsion With CTV To Treat Lung Carcinoma

摘要: 原发性肺癌共80例, 随机分为三组:榄香烯乳单药组24例, 客现有效率为29.2％, 生活质量改善率为54.2％; CTV方案化疗组29例, 客观有效率为34.50％, 生活质量改善率为31.0％, 但骨髓抑制明显; 榄香烯乳加CTV方案联合治疗组27例, 有效率达48.1％, 生活质量改善率达66.70％, 均较CTV方案化疗组明显提高(P<0.05), 且白细胞减少症发生率和毒性程度明显减轻。以上表明, 榄香烯乳合并CTV方案化疗可以起到增效减毒作用, 可能是治疗肺癌的新的优选方案。

Abstract: The 80 cases with primary lung cancer were treated, dividing randomly into threegroups:Elemene emulsion regime group inclouded 24 cases, objective remission rate(Orr) was 29.1%, improve rate of quality of life (QOL) was 54.2%; CTVchemotherapy group inclouded 29 cases, ORR was 34.5%, improve rate of QLO was 31.0%, but bone marrow depression was obvious; Elemene emulsion plus CTVchemotherapy group inclouded 27 cases, ORR was 48.1%, improve rate of QOL was66.7%. These two rates were significantly higher than those of CTV chemotherapygroup(P<0.05), and the degree of bone marrow depression was decreased. It can beeoncluded that elemene emulsion plus CTV chemotherapy maybe a new effective andsafe regime for lung carcinoma.