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鼻咽癌放疗患者血清结合唾液酸含量的动态研究[J]. 肿瘤防治研究, 1999, 26(6): 428-429.
引用本文: 鼻咽癌放疗患者血清结合唾液酸含量的动态研究[J]. 肿瘤防治研究, 1999, 26(6): 428-429.
Dynamic Changes of Lipid Bound Sialic Acid Levels in Patients with NasopharyNgeal Carcinoma Treated with Radiotherapy[J]. Cancer Research on Prevention and Treatment, 1999, 26(6): 428-429.
Citation: Dynamic Changes of Lipid Bound Sialic Acid Levels in Patients with NasopharyNgeal Carcinoma Treated with Radiotherapy[J]. Cancer Research on Prevention and Treatment, 1999, 26(6): 428-429.

鼻咽癌放疗患者血清结合唾液酸含量的动态研究

Dynamic Changes of Lipid Bound Sialic Acid Levels in Patients with NasopharyNgeal Carcinoma Treated with Radiotherapy

  • 摘要: 目的 探讨鼻咽癌放疗患者血清结合唾液含量对鼻咽癌放疗的监测作用。 方法 用改良硫代巴比妥显色法检测了43例鼻咽癌患者的血清结合唾液酸(LSA)含量及放疗后的改变。 结果 鼻咽癌患者血清LSA含量为256.92±57.02mg/1明显高于正常对照。Ⅰ、ⅡⅢ期的LSA含量分别为194.50±61.30mg/1、247.63±47.13mg/1、286.79±50.37mg/1,呈明显正相关(r=0.996)。放疗后血清LSA水平明显下降(P<0.001),其中未分化癌的LSA阴转率为81.87%,低分化癌为43.75%,有显著性差异。 结论 血清LSA作为鼻咽癌的一种标记物与其病变程度有关,对疗效追踪、监测病情变化有一定临床意义。

     

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