激光对荷瘤小鼠免疫系统影响的实验研究

Effect of Laser on IL- 6, IL- 8 and IL- 1 in Mice with Tumor

摘要: 目的: 借助于低能量的He-Ne激光激活免疫机制, 抑制肿瘤的生长。方法: 采用双抗体夹心ELISA法及MTT法对荷瘤小鼠激光照射前后细胞因子（TL-1、IL-6、IL-8）的含量进行检测, 并对其抑制肿瘤作用进行研究。结果: 激光照射瘤鼠脾区具有促进IL-1、IL-8产生, 抑制IL-6及瘤细胞增殖的作用。与对照组相比有非常显著差异(P<0.01)。结论: 低能量激光照射具有调节患瘤鼠白细胞介素产生及抗肿瘤作用。

Abstract: To observe the effect of cyto laser on immulogical mechanism. Methods: Double antibody sandwith enzyme linked immunosorbent assay( ELISA) and MIT test were used to measure the effect of laser on IL6, IL8 and IL1 tumor-bearing mice, Results: When laser acted on spleen region, promoting IL-1 and IL-8 production and suppressing IL-6 production, compared with control group showed very significant changes ( P<0.01) Conclusion: Laser has regulating effect of interleukin production and antitumor action.