放疗加化疗治疗晚期鼻咽癌的临床分析

Clinical Analysis of Treatment for Advanced Nasopharyngeal Carcinoma with Radiotherapy Plus Chemotherapy

摘要: 目的　评价综合治疗晚期鼻咽癌的疗效。方法　 1 993年 3月至 1 996年 3月, 1 88例、 a期鼻咽癌患者随机分为两组 (化放组和放疗组 ), 每组 94例。放疗用 60 Co机或直线加速器照射。鼻咽癌原发灶 DT68～ 76Gy/7- 7.5 w,颈部 DT5 0～ 70 Gy/5 - 7w。化疗组在放疗前和放疗后分别用 PDD+ 5 - Fu方案化疗。结果　 3、5年生存率放化疗组分别为 68.1 %、5 5 .3%, 放疗组分别为 5 4 .2 %、37.2 % ;远处转移率化放组为 35 .1 %, 放疗组为 47.9%, 统计学上都有显著性差异 ( P<0 .0 5 )。结论　放疗加化疗能提高晚期鼻咽癌的生存率并能降低远处转移率.

Abstract: Objective TO evaluate effect of radiotherapy plus chemotherapy in advanced nasopharyngeal carcinoma. Methods From March 1993 to March 1996,188 patients in Ⅲ?Ⅳa stage were divided randomly into two groups.Radiotherapy group (94 cases) was only treated by cobalt 60 or linear accelerator with D T68~76GY/7 7.5w in nasopharynx and D T50~70GY/5 7w in the neck.Chemo radiotherapy therapy group(94 cases) received chemotherapy with PDD+5 Fu before radiotherapy and after rediotherapy. Results The 3?5 year survival...