食管癌腔内放射治疗剂量学的临床研究

The dose clinical research of esopageal carcinoma brachytherapy

摘要: 目的　食管癌腔内放射治疗与单纯外照射的疗效比较。方法　对 2 80例食管癌患者采用随机分为腔内加体外照射 4组, 观察研究腔内治疗的急性食管反应及生存率。结果　A、B两组急性食管反应较重。 1、3、5年生存率A组 48%, 2 0 %, 8% ;B组 5 2 %, 2 2 %, 1 0 % ;C组 76%, 46%, 2 6% ;D组 70 %, 3 2 %, 2 0 % ;E组 5 7.5 %, 2 3 .8%, 1 5 %。1、3年C组较A、B、E组有显著差异 (P <0 .0 5 )。 5年C组较A、B组有显著差异 (P <0 .0 5 )。结论　C组较为理想, 是腔内加外照射目前可行的一种治疗方法。

Abstract: Objective To compare the effect between rachycherapy with radio therapy for esophageal carcinoma rate. Methods 280 patients were randomized into four groups. To observe the acate reaction fo brachycherapy and survival rate . Results The 1-3-5 year survival rate of A, B, C, D, E groups were 48%, 20%, 8% and 52%, 22%, 10%, and 76%, 46%, 26%, and 70%, 32%, 20%, and 57.5%, 23.8%, 15%respectively . The 1-3 year survival rates in C and A, B, E groups have a significant difference ( P <0.0...