OPG、OPGL在骨肉瘤中的表达及其意义

Expressions of OPG and OPGL in Osteosarcoma and Their Significance

摘要: 目的探讨OPG及OPGL在骨肉瘤中的表达及意义。方法采用免疫组化方法研究骨肉瘤、骨软骨瘤中OPG、OPGL的表达并分析其差异性。结果骨肉瘤与骨软骨瘤OPG的表达有显著性差异,骨肉瘤与骨软骨瘤OPGL的表达无显著性差异。结论骨肉瘤中存在OPG高表达,可能与骨肉瘤的成骨性有关。

Abstract: Objective To investigate the expression of OPG and OPGL in osteosarcoma and its significance. Methods The expression of OPG and OPGL in human osteosarcoma tissue,osteochondroma was detected by immunohistochemistry. Results The expressing rate of OPG was significant different between osteosarcoma and osteochondroma.The expressing rate of OPG was not significant different between osteosarcoma and osteochondroma. Conclusion There was overexpression of OPG in human osteosarcoma.The expression of OPG may have a clo...