地榆升白片预防老年NSCLC患者术后辅助化疗中的骨髓抑制
Clinical Study on Diyushengbai Tablet to Prevent Blood Cell Reduction of Postoperative NSCLC Elder Patients with Adjuvant Chemotherapy
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摘要: 目的观察评价地榆升白片(强力升白片)在预防老年非小细胞肺癌(NSCLC)患者术后辅助化疗中对骨髓抑制的影响。方法78例手术切除的NSCLC患者,随机分成治疗组(强力升白片+化疗)和对照组(利血生+化疗),化疗前、化疗结束后及化疗结束后1、2周查外周血白细胞水平。结果化疗结束后,治疗组及对照组骨髓抑制发生率分别为20.00%和27.63%,两组比较无统计学差异(P>0.05);化疗结束后1、2周两组骨髓抑制发生率分别为22.50%、33.55%和9.38%、17.11%,两组比较均有显著性差异(P<0.05)。结论地榆升白片升高白细胞的作用显著,可有效预防并减轻老年非小细胞肺癌患者术后辅助化疗中的骨髓抑制,明显提高患者的化疗耐受性。Abstract: Objective The objective of this study is to evaluate the effect of diyushengbai tablet on the blood cell count of postoperative NSCLC patients with adjuvant chemotherapy. Methods The patients were randomized into two groups: the test group consisted of 40 patients treated with a combination of diyushengbai tablet and MVP chemotherapy,the control group comprised 38 patients treated with lixuesheng tablet and MVP chemotherapy.The patients were evaluated to white blood cell before and 1,2 weeks after treatment....
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